I. BASIC CONSIDERATIONS -- 1. Anatomy and Physiology of Somatosensory and Pain Processing -- 2. The Neurochemistry of Somatosensory and Pain Processing -- 3. Taxonomy: Definition of Pain Terms and Chronic Pain Syndromes -- II. CLINICAL EVALUATION AND DIAGNOSTIC EXAMINATIONS -- 4. Physical Examination of the Patient with Pain -- 5. Pain Assessment -- 6. Psychologic Evaluation and Testing -- 7. Neurophysiologic Testing for Pain -- 8. Anatomy, Imaging and Common Pain Generating Degenerative Pathologies of the Spine -- 9. Determination of Disability -- III. PHARMACOLOGY AND PHARMACOLOGIC MODALITIES -- 10. Opioid Receptors -- 11. Major Opioids in Pain Management -- 12. Minor and Short-Acting Opioids -- 13. Opioid Therapy: Adverse Effects Including Addiction -- 14. Psychopharmacology for Pain Medicine -- 15. Membrane Stabilizers -- 16. Nonsteroidal Antiinflammatory Drugs and COX-2 Selective Inhibitors -- 17. Muscle Relaxants -- 18. Drugs for the Interventional Physician: Botulinum Toxin, Steroids, Radiopaque Dye -- IV. THERAPEUTIC INTERVENTIONS -- 19. Diagnostic Nerve Blocks -- 20. Neurosurgical Procedures for Treatment of Intractable Pain -- 21. Physical Medicine and Rehabilitation Approaches to Pain Management -- 22. Acupuncture -- 23. Psychological Interventions For Chronic Pain -- 24. Substance Use Disorders and Detoxification -- V. PERIOPERATIVE PAIN MANAGEMENT -- 25. Pain Management in the Emergency Department -- 26. Preemptive Analgesia: Physiology and Clinical Studies -- 27. Patient-Controlled Analgesia -- 28. Intrathecal Opioid Injections for Postoperative Pain -- 29. Epidural Opioids for Postoperative Pain -- 30. Intraarticular and Intraperitoneal Opioids for Postoperative Pain -- 31. Pediatric Postoperative Pain -- 32. Pain Management During Pregnancy and Lactation -- 33. Pain Management in the Critically Ill Patient -- VI. CHRONIC PAIN SYNDROMES -- 34. Classification of Headache Disorders -- 35. Migraine Headache and Cluster Headache -- 36. Tension Type Headache, Chronic Tension Headache and Other Chronic Headache Types -- 37. Postdural Puncture Headache and Spontaneous Intracranial Hypotension -- 38. Cervicogenic Headache and Orofacial Pain -- 39. An Overview of Low Back Pain Disorders -- 40. Interlaminar Epidural Steroid Injections for Lumbosacral Radiculopathy -- 41. Selective Nerve Root Blocks and Transforaminal Epidural Steroid Injections -- 42. Facet Joint Pain: Facet Joint Injections and Facet Rhizotomy -- 43. Pain Originating from the Buttock: Sacroiliac Joint Dysfunction and Piriformis Syndrome -- 44. Myofascial Pain Syndrome -- 45. Fibromyalgia -- 46.Complex Regional Pain Syndrome (CRPS): Terminology and Pathophysiology -- 47.Complex Regional Pain Syndrome (CRPS): Diagnosis, and Treatment -- 48. Herpes Zoster and Postherpetic Neuralgia -- 49. Phantom Pain -- 50. Central Pain States -- 51. Visceral Pain and Pelvic Pain -- 52. Sickle Cell Anemia -- 53. Diabetic and Other Peripheral Neuropathies -- 54. Entrapment Neuropathies -- 55. Chronic Pain Management in Children -- 56. Geriatric Pain -- VII. INTERVENTIONAL TECHNIQUES FOR PAIN MANAGEMENT -- 57. Spinal Cord Stimulation -- 58. Implanted Drug Delivery Systems for Control of Chronic Pain -- 59. Discography -- 60. Intradiscal Techniques: Intradiscal Electrothermal Coagulation (IDET) and Nucleoplasty -- 61. Osteoporosis and Percutaneous Vertebroplasty -- 62. Issues in Fluoroscopy: Advantages of Fluoroscopy, Radiation Safety -- VIII. CANCER PAIN -- 63. Pharmacologic Management of Cancer Pain -- 64. Management of Pain at End of Life -- 65. Visceral Neurolytic Sympathetic Blocks -- 66. Intrathecal and Epidural Neurolysis: Agents Used for Neurolytic Block -- IX. LOCAL ANESTHETICS AND NERVE BLOCKADE -- 67. Local Anesthetics -- Clinical Aspects -- 68. Spinal Anesthesia -- 69. Epidural Anesthesia -- 70.Combined Spinal-Epidural Technique -- 71. Caudal Anesthesia -- 72. Head and Neck Blocks -- 73. Brachial Plexus Block: Techniques Above the Clavicle -- 74. Brachial Plexus Block: Techniques Below the Clavicle -- 75. Truncal Blocks: Intercostal, Paravertebral, Interpleural, Suprascapular, Ilioinguinal, and Iliohypogastric Nerve Blocks -- 76. Lumbar Plexus, Femoral, Lateral Femoral Cutaneous, Obturator, Saphenous, and Fascia Iliaca Blocks -- 77. Sciatic Nerve Block -- 78. Ankle Block -- 79. Issues in Peripheral Nerve Blocks: Use of Nerve Stimulators, Multiple Versus Single Injection Techniques, and Use of Adjuvants -- 80. Peripheral Sympathetic Blocks -- 81.Complications After Peripheral Nerve Blockade -- 82.Complications After Neuraxial Blockade -- 83. Anticoagulants and Neuraxial Injections.