History of Pediatric Critical Care -- The Intensivist in the New Hospital Environment: Patient Care and Stewardship of Hospital Resources -- The Nurse in Pediatric Critical Care -- Research in Pediatric Critical Care -- Proving the Point: Evidence-Based Medicine in Pediatric Critical Care -- Outcomes in Pediatric Critical Care Medicine: Implications for Health Services Research and Patient Care -- Safety and Quality Assessment in the Pediatric Intensive Care Unit -- Information Technology in Critical Care -- Family-Centered Care in the Pediatric Intensive Care Unit -- Ethics in Pediatric Intensive Care -- Ethical Issues in Death and Dying -- Palliative Care -- The Process of Organ Donation and Pediatric Donor Management -- Pediatric Transport: Shifting the Paradigm to Improve Patient Outcome -- Pediatric Vascular Access and Centeses -- Pediatric Intensive Care in Developing Countries -- Educating the Intensivist -- Critical Care in Public Health Emergencies -- Structure and Function of the Heart -- Regional Circulation -- Principles of Invasive Monitoring -- Assessment of Cardiovascular Function -- Echocardiography and Noninvasive Diagnosis -- Diagnostic and Therapeutic Cardiac Catheterization -- Pharmacology of the Cardiovascular System -- Cardiopulmonary Interactions -- Myocardial Dysfunction, Ventricular Assist Devices, and Extracorporeal Life Support -- Disorders of Cardiac Rhythm -- Shock States -- Cardiac Bypass for Repair of Congenital Heart Disease in Infants and Children -- Critical Care After Surgery for Congenital Cardiac Disease -- Cardiac Transplantation -- Physiologic Foundations of Cardiopulmonary Resuscitation -- Performance of Cardiopulmonary Resuscitation in Infants and Children -- Structure and Development of the Upper Respiratory System in Infants and Children.

Structure of the Respiratory System: Lower Respiratory Tract -- Physiology of the Respiratory System -- Control of Breathing and Acute Respiratory Failure -- Assessment and Monitoring of Respiratory Function -- Overview of Breathing Failure -- Ventilation/Perfusion Inequality -- Mechanical Dysfunction of the Respiratory System -- Noninvasive Monitoring in Children -- Specific Diseases of the Respiratory System: Upper Airway -- Asthma -- Neonatal Respiratory Disease -- Pneumonitis and Interstitial Disease -- Diseases of Pulmonary Circulation -- Mechanical Ventilation and Respiratory Care -- Noninvasive Ventilation: Concepts and Practice -- Ventilator-Induced Lung Injury -- Acute Respiratory Distress Syndrome in Children -- Extracorporeal Life Support -- Pediatric Neurocritical Care -- Pediatric Neurologic Assessment and Monitoring -- Neuroimaging -- Structure, Function, and Development of the Nervous System -- Coma and Depressed Sensorium -- Intracranial Hypertension and Brain Monitoring -- Status Epilepticus -- Severe Traumatic Brain Injury in Infants and Children -- Hypoxic-Ischemic Encephalopathy: Pathobiology and Therapy of the Post-Resuscitation Syndrome in Children -- Stroke and Intracerebral Hemorrhage -- Acute Neuromuscular Diseases and Disorders -- Central Nervous System Infections Presenting to the Pediatric Intensive Care Unit -- Renal Structure and Function -- Fluid and Electrolyte Issues in Pediatric Critical Illness -- Acid-Base Balance and Disorders -- Tests of Kidney Function in Children -- Renal Pharmacology -- Glomerulotubular Dysfunction and Acute Kidney Injury -- Pediatric Renal Replacement Therapy in the Intensive Care Unit -- Hypertension in the Pediatric Intensive Care Unit -- Cellular Respiration -- Nutrient Metabolism and Nutrition Therapy During Critical Illness.

Inborn Errors of Metabolism -- Common Endocrinopathies in the Pediatric Intensive Care Unit -- Diabetic Ketoacidosis -- Structure and Function of Hematopoietic Organs -- Thrombosis in Pediatric Intensive Care -- Hematology and Oncology Problems in the Intensive Care Unit -- Transfusion Medicine -- Critical Illness Involving Children Undergoing Hematopoietic Progenitor Cell Transplantation -- Hemoglobinopathies -- Gastrointestinal Structure and Function -- Disorders and Diseases of the Gastrointestinal Tract and Liver -- Gastrointestinal Pharmacology -- Acute Liver Failure, Liver Transplantation, and Extracorporeal Liver Support -- Acute Abdomen -- The Innate Immune System -- Infection and Host Response -- Congenital Immunodeficiencies -- Acquired Immune Dysfunction -- Bacterial Infection, Antimicrobial Use, and Antibiotic-Resistant Organisms in the Pediatric Intensive Care Unit -- Life-Threatening Viral Diseases and Their Treatment -- Infectious Syndromes in the Pediatric Intensive Care Unit -- Health Care-Associated Infection in the Pediatric Intensive Care Unit: Epidemiology and Control-Keeping Patients Safe -- Autoimmune Diseases: Diagnosis, Treatment, and Life-Threatening Complications -- Genomic and Proteomic Medicine in Critical Care -- Molecular Foundations of Cellular Injury: Necrosis, Apoptosis, and Autophagy -- Endotheliopathy -- Neuroendocrine-Immune Mediator Coordination and Disarray in Critical Illness -- Sepsis -- Inflammation and Immunity: Systemic Inflammatory Response Syndrome, Sepsis, Acute Lung Injury, and Multiple Organ Failure -- Principles of Toxin Assessment and Screening.

Toxidromes and Their Treatment -- Bites and Stings -- Heat Injury -- Accidental Hypothermia -- Drowning -- Burn and Inhalation Injuries -- Evaluation, Stabilization, and Initial Management After Multiple Trauma -- Child Abuse and Neglect -- Thoracic Injuries in Children -- Abdominal Trauma in Pediatric Critical Care -- Principles of Drug Disposition in the Critically Ill Child -- Molecular Mechanisms of Drug Actions: From Receptors to Effectors -- Adverse Drug Reactions and Drug-drug Interactions -- Airway Management -- Organ System Considerations that Affect Anesthetic Management -- Anesthesia Principles and Operating Room Anesthesia Regimens -- Neuromuscular Blocking Agents -- Sedation and Analgesia -- Malignant Hyperthermia.